Nalidixic acid sodium salt

  • CAS：3374-05-8
  • purity：99%
Inquiry

Details

Chemical plants supply high-quality Nalidixic acid sodium salt 3374-05-8 in bulk

  • Molecular Formula:C12H12 N2 O3 . Na
  • Molecular Weight:254.221
  • Appearance/Colour:white to off-white powder 
  • Vapor Pressure:1.45E-07mmHg at 25°C 
  • Melting Point:>280℃ 
  • Boiling Point:413.1°Cat760mmHg 
  • Flash Point:203.6°C 
  • PSA：75.02000 
  • Density:1.331g/cm3 
  • LogP:0.08830 

Nalidixic acid sodium salt(Cas 3374-05-8) Usage

Biochem/physiol Actions

Nalidixic acid sodium salt is an inhibitor of bacterial DNA polymerase (DNA gyrase) and avian myeloblastoma virus reverse transcriptase. Inhibits nucleic acid and protein synthesis in Saccharomyces cerevisiae.

InChI:InChI=1/C12H12N2O3.Na/c1-3-14-6-9(12(16)17)10(15)8-5-4-7(2)13-11(8)14;/h4-6H,3H2,1-2H3,(H,16,17);/q;+1/p-1

3374-05-8 Relevant articles

Structural and morphological aspects of (fluoro)quinolone delivery by layered double hydroxide nanoparticles

Salguero, Yadira,García, Mónica Cristina,Mosconi, Giuliana,Rojas, Ricardo

, p. 19144 - 19152 (2018)

Layered double hydroxides (LDHs) have be...

Synthesis, thermal behavior, and spectroscopic study of the solid nalidixate of selected light trivalent lanthanides

Dobies Návia, Marcos Vinícius,Alves Gálico, Diogo,Junior Caires, Flávio,Marques Luiz, José,Spezia Nunes, Ronaldo

, p. 1717 - 1727 (2018)

Solid-state [Ln(nal)3]·nH2O compounds, w...

3374-05-8 Process route

nalidixic Acid
389-08-2

nalidixic Acid

nalidixic acid, sodium salt
3374-05-8

nalidixic acid, sodium salt

Conditions
Conditions Yield
With sodium hydroxide; In water; pH=8.5; Reagent/catalyst;
With sodium hydroxide; In water;
ethanol
64-17-5

ethanol

nalidixic acid, sodium salt
3374-05-8

nalidixic acid, sodium salt

ethyl 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate
33331-59-8

ethyl 1-ethyl-7-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylate

Conditions
Conditions Yield
With toluene-4-sulfonic acid; In chloroform; Dean-Stark;
55%

3374-05-8 Upstream products

  • 389-08-2
    389-08-2

    nalidixic Acid

3374-05-8 Downstream products

  • 115622-62-3
    115622-62-3

    <2R-(2α,6α,7β)>-3-<<<(1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridin-3-yl)carbonyl>oxy>methyl>-8-oxo-7-<(phenoxyacetyl)amino>-5-thia-1-azabicyclo<4.2.0>oct-3-ene-2-carboxylic acid

  • 122949-35-3
    122949-35-3

    <2R-(2α,6α,7β)>-3-<<<(1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridin-3-yl)carbonyl>oxy>methyl>-8-oxo-7-<(phenoxyacetyl)amino>-5-thia-1-azabicyclo<4.2.0>oct-3-ene-2-carboxylic acid (4-nitrophenyl)methyl ester

  • 122949-45-5
    122949-45-5

    (6R-trans)-3-<<<(1-ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridin-3-yl)carbonyl>oxy>methyl>-8-oxo-7-<(phenoxyacetyl)amino>-5-thia-1-azabicyclo<4.2.0>oct-2-ene-2-carboxylic acid (4-nitrophenyl)methyl ester

  • 115653-76-4
    115653-76-4

    1-Ethyl-7-methyl-4-oxo-1,4-dihydro-[1,8]naphthyridine-3-carboxylic acid (6R,7R)-2-tert-butoxycarbonyl-7-{2-[(Z)-methoxyimino]-2-[2-(trityl-amino)-thiazol-4-yl]-acetylamino}-8-oxo-5-thia-1-aza-bicyclo[4.2.0]oct-2-en-3-ylmethyl ester

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