Details
Manufacturer supply high quality 2-Heptynoic acid 1483-67-6 with ISO standards
- Molecular Formula: C7H10 O2
- Molecular Weight: 126.155
- Vapor Pressure: 0.0127mmHg at 25°C
- Melting Point: -3.32°C (estimate)
- Refractive Index: 1.4590-1.4620
- Boiling Point: 240.5°Cat760mmHg
- PKA: 2.67±0.10(Predicted)
- Flash Point: 113.5°C
- PSA： 37.30000
- Density: 1.033g/cm3
- LogP: 1.26460
2-Heptynoic acid(Cas 1483-67-6) Usage
|
Synthesis Reference(s) |
Journal of the American Chemical Society, 78, p. 1221, 1956 DOI: 10.1021/ja01587a037 |
InChI:InChI=1/C7H10O2/c1-2-3-4-5-6-7(8)9/h2-4H2,1H3,(H,8,9)
1483-67-6 Relevant articles
-
Khan,G.R. et al.
, p. 215 - 216 (1979)
-
-
Koehl,Wenzke
, p. 1418 (1937)
-
Cis -1,2-Bis(diphenylphosphino)ethylene copper(i) catalyzed C-H activation and carboxylation of terminal alkynes
Trivedi, Manoj,Smreker, Jacob R.,Singh, Gurmeet,Kumar, Abhinav,Rath, Nigam P.
, p. 14145 - 14151 (2017)
The reaction of cis-1,2-bis(diphenylphos...
-
Haynes,Jones
, p. 503,505 (1946)
-
A Schiff base-modified silver catalyst for efficient fixation of CO2 as carboxylic acid at ambient pressure
Wu, Zhilian,Sun, Lei,Liu, Qinggang,Yang, Xiaofeng,Ye, Xue,Hu, Yancheng,Huang, Yanqiang
, p. 2080 - 2085 (2017)
The fixation of CO2 as a carboxylic acid...
Microwave-assisted fabrication of a mixed-ligand [Cu4(μ3-OH)2]-cluster-based metal–organic framework with coordinatively unsaturated metal sites for carboxylation of terminal alkynes with carbon dioxide
Wang, Wen-Jing,Sun, Zhong-Hua,Chen, Sheng-Chun,Qian, Jun-Feng,He, Ming-Yang,Chen, Qun
, (2021/05/24)
The development of efficient and stable ...
Organocatalytic Strategy for the Fixation of CO2via Carboxylation of Terminal Alkynes
Shi, Jun-Bin,Bu, Qingqing,Liu, Bin-Yuan,Dai, Bin,Liu, Ning
, p. 1850 - 1860 (2021/01/14)
An organocatalytic strategy for the dire...
Method for rapidly preparing acetylenic acid and derivatives thereof based on microchannel continuous flow technology
-
Paragraph 0027, (2021/05/19)
The invention discloses a method for rap...
Fixation of CO2 as a carboxylic acid precursor by microcrystalline cellulose (MCC) supported Ag NPs: A more efficient, sustainable, biodegradable and eco-friendly catalyst
Shah, Dharmesh J.,Sharma, Anuj S.,Shah, Akshara P.,Sharma, Vinay S.,Athar, Mohd,Soni, Jigar Y.
supporting information, p. 8669 - 8676 (2019/06/14)
Silver nanoparticles supported on microc...
1483-67-6 Process route
-
-
124-38-9,18923-20-1
carbon dioxide
-
-
693-02-7
hex-1-yne
-
-
1483-67-6
hept-2-ynoic acid
| Conditions | Yield |
|---|---|
|
With
hydrogenchloride; C54H44Cu2N2P4S2; caesium carbonate;
In
N,N-dimethyl-formamide;
at 25 ℃;
for 12h;
Inert atmosphere;
|
95%
|
|
With
caesium carbonate;
In
dimethyl sulfoxide;
at 60 ℃;
for 24h;
under 760.051 Torr;
Green chemistry;
|
94%
|
|
With
caesium carbonate;
In
N,N-dimethyl-formamide;
at 24 ℃;
for 20h;
|
92%
|
|
With
3-(1-mesityl-1H-imidazol-3-ium-3-yl)propane-1-sulfonate; caesium carbonate; potassium iodide; silver(l) oxide;
In
N,N-dimethyl-formamide;
at 35 ℃;
for 24h;
under 750.075 Torr;
Darkness;
|
92%
|
|
carbon dioxide; hex-1-yne;
With
caesium carbonate;
In
N,N-dimethyl-formamide;
at 120 ℃;
for 18h;
under 1900.13 Torr;
With
hydrogenchloride; water;
In
N,N-dimethyl-formamide;
pH=1;
|
90%
|
|
With
n-butyllithium;
In
tetrahydrofuran; hexane;
at -78 - 0 ℃;
for 1.25h;
Inert atmosphere;
|
87%
|
|
With
caesium carbonate;
In
dimethyl sulfoxide;
at 50 ℃;
for 16h;
under 760.051 Torr;
Sealed tube;
|
87%
|
|
carbon dioxide; hex-1-yne;
With
caesium carbonate;
N,N,N,N,-tetramethylethylenediamine; copper(l) chloride;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 24h;
under 760.051 Torr;
With
hydrogenchloride;
In
dichloromethane; water;
pH=1;
Product distribution / selectivity;
|
85%
|
|
With
1,3-bis(4-methylbenzyl)imidazol-2-ylidene silver(I) chloride; caesium carbonate;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 16h;
under 760.051 Torr;
Schlenk technique;
|
79%
|
|
With
{[Cu4(μ3-OH)2(atrz)2(SIP)2]?4H2O}n; caesium carbonate;
In
N,N-dimethyl-formamide;
at 100 ℃;
for 16h;
under 2250.23 Torr;
Autoclave;
|
71%
|
|
carbon dioxide; hex-1-yne;
With
caesium carbonate; silver(I) iodide;
In
N,N-dimethyl-formamide;
at 50 ℃;
for 12h;
under 1500.15 Torr;
Autoclave;
With
hydrogenchloride;
In
water;
Cooling;
|
65%
|
|
carbon dioxide; hex-1-yne;
With
C24H30N3(1+)*Cl4Fe; caesium carbonate;
In
N,N-dimethyl-formamide;
at 70 ℃;
for 20h;
under 760.051 Torr;
With
hydrogenchloride; water;
In
N,N-dimethyl-formamide;
at 20 ℃;
|
58%
|
|
With
1-(6-acetylpyridin-2-yl)-3-propyl-1H-benzo[d]imidazol-3-ium iodide;
In
dimethyl sulfoxide;
at 60 ℃;
for 24h;
under 760.051 Torr;
|
58%
|
|
Multistep reaction;
(i) Cs, heptane, THF, (ii) /BRN= 1900390/;
|
|
|
Multistep reaction;
(i) nBuLi, (ii) /BRN= 1900390/, (iii) aq. H2SO4;
|
|
|
Multistep reaction;
(i) NaAlH4, H2, diglyme, (ii) /BRN= 1900390/;
|
|
|
hex-1-yne;
With
n-butyllithium;
In
tetrahydrofuran;
at -78 - -30 ℃;
for 1.5h;
Inert atmosphere;
carbon dioxide;
In
tetrahydrofuran;
at -78 - 25 ℃;
for 1.5h;
Inert atmosphere;
|
|
|
hex-1-yne;
With
n-butyllithium;
In
tetrahydrofuran;
at -78 ℃;
for 1h;
Inert atmosphere;
Schlenk technique;
carbon dioxide;
In
tetrahydrofuran;
at 0 ℃;
Inert atmosphere;
Schlenk technique;
|
|
|
hex-1-yne;
With
n-butyllithium;
In
tetrahydrofuran;
at -10 - 0 ℃;
for 0.00416667h;
carbon dioxide;
In
tetrahydrofuran;
at 10 - 20 ℃;
for 3.05556E-05h;
|
-
-
16930-95-3
ethyl hept-2-ynoate
-
-
1483-67-6
hept-2-ynoic acid
| Conditions | Yield |
|---|---|
|
With
water; sodium hydroxide;
In
ethanol;
at 20 ℃;
for 2.5h;
Schlenk technique;
Sealed tube;
Inert atmosphere;
|
88%
|
|
With
water; sodium hydroxide;
In
ethanol;
at 20 ℃;
for 2.5h;
Inert atmosphere;
|
85%
|
|
With
sodium hydroxide; N-benzyl-N,N,N-triethylammonium chloride;
In
diethyl ether; water;
for 120h;
Yield given;
|
|
|
With
water; sodium hydroxide;
In
ethanol;
Inert atmosphere;
|
1483-67-6 Upstream products
-
18621-55-1
trideca-5,8-diyn-7-ol
-
124-38-9
carbon dioxide
-
17689-03-1
1-hexynyllithium
-
55944-49-5
1,3-dilithiohex-1-yne
1483-67-6 Downstream products
-
18937-78-5
methyl 2-heptynoate
-
16930-95-3
ethyl hept-2-ynoate
-
15719-64-9
methylammonium carbonate
-
693-02-7
hex-1-yne
