Details
Cost-effective and customizable 6-Nitroindoline 19727-83-4 in stock
- Molecular Formula: C8H8N2O2
- Molecular Weight: 164.164
- Appearance/Colour: orange crystalline powder or red crystals
- Vapor Pressure: 0.000762mmHg at 25°C
- Melting Point: 67-69 °C(lit.)
- Refractive Index: 1.608
- Boiling Point: 306.6 °C at 760 mmHg
- PKA: 3.39±0.20(Predicted)
- Flash Point: 139.3 °C
- PSA： 57.85000
- Density: 1.298 g/cm3
- LogP: 2.22400
6-Nitroindoline(Cas 19727-83-4) Usage
InChI:InChI=1/C8H8N2O2/c11-10(12)7-2-1-6-3-4-9-8(6)5-7/h1-2,5,9H,3-4H2
19727-83-4 Relevant articles
Discovery of N-indanyl benzamides as potent RORγt inverse agonists
Tian, Jinlong,Sun, Nannan,Yu, Mingcheng,Gu, Xianfeng,Xie, Qiong,Shao, Liming,Liu, Jin,Liu, Li,Wang, Yonghui
, p. 37 - 48 (2019)
The retinoic acid receptor-related orpha...
Palladium-Catalyzed Direct and Specific C-7 Acylation of Indolines with 1,2-Diketones
Xie, Guilin,Zhao, Yuhan,Cai, Changqun,Deng, Guo-Jun,Gong, Hang
supporting information, p. 410 - 415 (2021/01/26)
The indole scaffold is a ubiquitous and ...
The Relation Between Position and Chemical Composition of Bis-Indole Substituents Determines Their Interactions with G-Quadruplex DNA
Prasad, Bagineni,Das, Rabindra Nath,Jamroskovic, Jan,Kumar, Rajendra,Hedenstr?m, Mattias,Sabouri, Nasim,Chorell, Erik
supporting information, p. 9561 - 9572 (2020/07/09)
G-quadruplex (G4) DNA structures are lin...
Flexible Versus Rigid G-Quadruplex DNA Ligands: Synthesis of Two Series of Bis-indole Derivatives and Comparison of Their Interactions with G-Quadruplex DNA
Prasad, Bagineni,Jamroskovic, Jan,Bhowmik, Sudipta,Kumar, Rajendra,Romell, Tajanena,Sabouri, Nasim,Chorell, Erik
supporting information, p. 7926 - 7938 (2018/06/15)
Small molecules that target G-quadruplex...
19727-83-4 Process route
-
-
496-15-1
1-indoline
-
-
19727-83-4
6-nitroindoline
| Conditions | Yield |
|---|---|
|
With
sulfuric acid; potassium nitrate;
at 20 ℃;
for 1.25h;
|
95%
|
|
With
sodium hydroxide; nitric acid;
In
sulfuric acid;
|
95%
|
|
With
sulfuric acid; nitric acid;
at 20 ℃;
|
80%
|
|
With
sulfuric acid; nitric acid;
at 0 - 20 ℃;
|
80%
|
|
With
sulfuric acid; nitric acid;
at 0 - 20 ℃;
|
80%
|
|
With
sulfuric acid; uronium nitrate;
at -5 - 0 ℃;
|
71%
|
|
With
sulfuric acid; potassium nitrate;
at 0 - 20 ℃;
for 1.25h;
|
48.8%
|
|
With
sulfuric acid; nitric acid;
|
|
|
With
sulfuric acid; nitric acid;
at 0 ℃;
for 0.0833333h;
|
|
|
With
sulfuric acid; nitric acid;
|
|
|
With
sodium nitrate; sulfuric acid;
|
|
|
With
sodium nitrate; sulfuric acid;
|
-
-
4769-96-4
6-nitroindole
-
-
19727-83-4
6-nitroindoline
| Conditions | Yield |
|---|---|
|
With
trimethylamine-borane;
|
|
|
With
sodium cyanoborohydride; acetic acid;
at 0 ℃;
for 12h;
|
19727-83-4 Upstream products
-
496-15-1
1-indoline
-
7664-93-9
sulfuric acid
-
7697-37-2
nitric acid
-
4769-96-4
6-nitroindole
19727-83-4 Downstream products
-
19232-51-0
1-benzoyl-6-nitro-indoline
-
15918-79-3
indolin-6-amine
-
4769-96-4
6-nitroindole
-
22949-08-2
1-acetyl-6-nitro-2,3-dihydroindole
