Details
Factory Export Top Purity 6-Chloroindole-2-carboxylic acid 16732-75-5 In Stock
- Molecular Formula: C9H6ClNO2
- Molecular Weight: 195.605
- Vapor Pressure: 7.12E-09mmHg at 25°C
- Melting Point: 248-249 °C
- Refractive Index: 1.728
- Boiling Point: 449.7 °C at 760 mmHg
- PKA: 4.30±0.30(Predicted)
- Flash Point: 225.8 °C
- PSA： 53.09000
- Density: 1.548 g/cm3
- LogP: 2.51950
6-Chloroindole-2-carboxylic acid(Cas 16732-75-5) Usage
InChI:InChI=1/C9H6ClNO2/c10-6-2-1-5-3-8(9(12)13)11-7(5)4-6/h1-4,11H,(H,12,13)
16732-75-5 Relevant articles
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Fox,Bullock
, p. 2756,2758 (1951)
-
Synthesis, and evaluation of in vitro and in vivo anticancer activity of 14-substituted oridonin analogs: A novel and potent cell cycle arrest and apoptosis inducer through the p53-MDM2 pathway
Shen, Qing-Kun,Deng, Hao,Wang, Shi-Ben,Tian, Yu-Shun,Quan, Zhen-Shan
, p. 15 - 31 (2019/04/10)
A series of novel oridonin derivatives b...
Design, synthesis and structure-activity relationship studies of novel and diverse cyclooxygenase-2 inhibitors as anti-inflammatory drugs
Hayashi, Shigeo,Ueno, Naomi,Murase, Akio,Takada, Junji
, p. 846 - 867 (2015/02/19)
Because of the pivotal role of cyclooxyg...
AUTOTAXIN INHIBITORS AND USES THEREOF
-
Page/Page column 168, (2012/03/11)
Described herein are compounds that are ...
INDOLOYLGUANIDINE DERIVATIVES
-
, (2008/06/13)
-
16732-75-5 Process route
-
-
6828-35-9
5-chloro-2-iodoaniline
-
-
127-17-3
2-oxo-propionic acid
-
-
16732-75-5
6-chloro-1H-indole-2-carboxylic acid
| Conditions | Yield |
|---|---|
|
5-chloro-2-iodoaniline; 2-oxo-propionic acid;
With
1,4-diaza-bicyclo[2.2.2]octane;
for 0.333333h;
Inert atmosphere;
palladium diacetate;
at 110 ℃;
for 1h;
|
-
-
896137-74-9
6-chloro-1-(phenylsulfonyl)-1H-indole-2-carboxylic acid
-
-
16732-75-5
6-chloro-1H-indole-2-carboxylic acid
| Conditions | Yield |
|---|---|
|
6-chloro-1-(phenylsulfonyl)-1H-indole-2-carboxylic acid;
With
sodium hydroxide;
In
ethanol;
for 11h;
Reflux;
Inert atmosphere;
With
hydrogenchloride;
In
water;
|
95%
|
16732-75-5 Upstream products
-
71300-08-8
(4-chloro-2-nitro-phenyl)-pyruvic acid
-
27034-51-1
ethyl 6-chloro-1H-indole-2-carboxylate
-
89-59-8
4-chloro-2-nitrotoluene
-
540523-98-6
3-(4-chloro-2-nitro-phenyl)-2-oxo-propionic acid ethyl ester
16732-75-5 Downstream products
-
17422-33-2
6-chloroindole
-
27034-51-1
ethyl 6-chloro-1H-indole-2-carboxylate
-
98081-84-6
6-chloro-2-methoxycarbonylindole
-
43142-81-0
ethyl 6-chloro-1-methyl-1H-indole-2-carboxylate
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