Details
Cost-effective and customizable INDOLE-3-ACETIC ACID HYDRAZIDE 5448-47-5 supplier
- Molecular Formula:C10H11N3O
- Molecular Weight:189.217
- Appearance/Colour:beige to pale brown fine crystalline powder
- Vapor Pressure:7.76E-11mmHg at 25°C
- Melting Point:142-145 °C(lit.)
- Refractive Index:1.691
- Boiling Point:518 °C at 760 mmHg
- PKA:13.23±0.18(Predicted)
- Flash Point:267.1 °C
- PSA：70.91000
- Density:1.311 g/cm3
- LogP:1.79150
INDOLE-3-ACETIC ACID HYDRAZIDE(Cas 5448-47-5) Usage
InChI:InChI=1/C10H11N3O/c11-13-10(14)5-7-6-12-9-4-2-1-3-8(7)9/h1-4,6,12H,5,11H2,(H,13,14)
5448-47-5 Relevant articles
Synthesis and screening of some novel substituted indoles contained 1,3,4-oxadiazole and 1,2,4-triazole moiety
Gadegoni, Hemalatha,Manda, Sarangapani
, p. 127 - 130 (2013)
A series of novel 3-[5-(1H-indol-3-yl-me...
A new CDK2 inhibitor with 3-hydrazonoindolin-2-one scaffold endowed with anti-breast cancer activity: Design, synthesis, biological evaluation, and in silico insights
Al-Sanea, Mohammad M.,Obaidullah, Ahmad J.,Shaker, Mohamed E.,Chilingaryan, Garri,Alanazi, Mohammed M.,Alsaif, Nawaf A.,Alkahtani, Hamad M.,Alsubaie, Sultan A.,Abdelgawad, Mohamed A.
, (2021)
Background: Cyclin-dependent kinases (CD...
Synthesis of 5-[(1H-indol-3-yl)methyl]-1,3,4-oxadiazole-2(3H)-thiones and their protective activity against oxidative stress
I?kauskien?, Monika,Kadlecová, Alena,Voller, Ji?í,Janovská, Lucie,Malinauskien?, Vida,?ukauskait?, Asta,?a?kus, Algirdas
, (2021/03/29)
A small library of 2-[(1H-indol-3-yl)met...
Synthesis of new urease enzyme inhibitors as antiulcer drug and computational study
Taha, Muhammad,Ismail, Sukinah,Imran, Syahrul,Almandil, Noor Barak,Alomari, Munther,Rahim, Fazal,Uddin, Nizam,Hayat, Shawkat,Zaman, Khalid,Ibrahim, Mohamad,Alghanem, Bandar,Islam, Imadul,Farooq, Rai Khalid,Boudjelal, Mohamed,Khan, Khalid Mohammed
, (2021/04/26)
In search of potent urease inhibitor ind...
Diversity-oriented synthesis and antifungal activities of novel pimprinine derivative bearing a 1,3,4-oxadiazole-5-thioether moiety
Song, Zi-Long,Zhu, Yun,Liu, Jing-Rui,Guo, Shu-Ke,Gu, Yu-Cheng,Han, Xinya,Dong, Hong-Qiang,Sun, Qi,Zhang, Wei-Hua,Zhang, Ming-Zhi
, p. 205 - 221 (2020/02/18)
Abstract: Based on the strategy of diver...
Synthesis, Pharmacological Evaluation and Molecular Docking Studies of N-[2-(1H-indol-3-yl)Acetyl]Arylsulfonohydrazides
Abbasi, M. A.,Ahmad, I.,Ashraf, M.,Aziz-ur-Rehman,Fatima, Hina,Khan, F. A.,Lodhi, M. A.,Qurat-ul-Ain,Rubab, K.,Shah, S. A. A.,Shahid, M.,Siddiqui, S. Z.
, p. 665 - 678 (2021/10/30)
Synthesis of heterocyclic compounds enco...
5448-47-5 Process route
-
-
1912-33-0
Indole-3-acetic acid methyl ester
-
-
5448-47-5
1H-indol-3-acetohydrazide
| Conditions | Yield |
|---|---|
|
With
hydrazine hydrate;
In
methanol;
at 60 ℃;
|
100% |
|
With
hydrazine hydrate;
Microwave irradiation;
|
87% |
|
With
hydrazine;
In
methanol;
|
85% |
|
With
hydrazine hydrate;
In
ethanol;
for 28h;
Heating;
|
68% |
|
With
hydrazine hydrate;
In
ethanol;
for 6h;
Heating;
|
66% |
|
With
hydrazine;
In
ethanol;
Reflux;
|
60% |
|
With
hydrazine hydrate;
In
ethanol;
Heating;
|
59% |
|
With
water; hydrazine hydrate;
|
|
|
With
ethanol; hydrazine hydrate;
|
|
|
With
hydrazine hydrate;
In
1,2-dimethoxyethane;
at 115 ℃;
for 20h;
|
9.2 g |
|
With
hydrazine hydrate;
In
ethanol;
for 3h;
Reflux;
|
|
|
With
hydrazine hydrate;
In
methanol; water;
for 16h;
Reflux;
|
|
|
With
hydrazine hydrate;
In
methanol;
for 6h;
Reflux;
|
-
-
778-82-5
ethyl 3-indoleacetate
-
-
5448-47-5
1H-indol-3-acetohydrazide
| Conditions | Yield |
|---|---|
|
With
hydrazine hydrate;
In
ethanol;
for 8h;
Reflux;
|
95% |
|
With
hydrazine hydrate;
In
ethanol;
Reflux;
|
95% |
|
With
hydrazine hydrate;
In
ethanol;
for 6h;
Reflux;
|
90% |
|
With
hydrazine hydrate;
In
methanol;
for 3h;
|
89% |
|
With
hydrazine hydrate;
In
ethanol;
for 4h;
Reflux;
|
85% |
|
With
hydrazine hydrate;
In
ethanol;
for 4h;
Heating;
|
80% |
|
With
hydrazine hydrate;
In
ethanol;
for 7h;
Reflux;
|
78% |
|
With
water; hydrazine hydrate;
|
|
|
With
ethanol; hydrazine hydrate;
|
|
|
With
hydrazine hydrate;
at 80 ℃;
|
|
|
With
hydrazine;
In
ethanol;
for 2h;
Reflux;
|
|
|
With
hydrazine hydrate;
In
ethanol;
Reflux;
|
5448-47-5 Upstream products
-
1912-33-0
Indole-3-acetic acid methyl ester
-
778-82-5
ethyl 3-indoleacetate
-
87-51-4
indole-3-acetic acid
-
120-72-9
indole
5448-47-5 Downstream products
-
15316-22-0
(E)-N'-benzylidene-2-(1H-indol-3-yl)acetohydrazide
-
13113-08-1
2-(2-(1H-indol-3-yl)acetamido)acetic acid
-
82380-73-2
2-phenyl-5-<(3'-indolyl)methyl>-1,3,4-oxadiazole
-
1191936-37-4
2-(1H-indol-3-yl)-N’-(4-methylbenzylidene)acetohydrazide
